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What is Sulfamethoxazole and trimethoprim?

Sulfamethoxazole and trimethoprim combination is used to treat infections such as urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery)

Sulfamethoxazole/Trimethoprim is used for:

Treating infections caused by certain bacteria.

Sulfamethoxazole/trimethoprim is an antibiotic combination containing a sulfonamide antibiotic. It works by killing sensitive bacteria.

Do NOT use sulfamethoxazole/ trimethoprim if:

1. you are allergic to any ingredient in sulfamethoxazole/trimethoprim or to any other sulfonamide (sulfa) medicine (eg, glipizide, hydrochlorothiazide)
2. you have a history of low blood platelet levels (immune thrombocytopenia) caused by trimethoprim or a sulfa medicine
3. you have liver damage or severe kidney problems
4. you have anemia caused by low levels of folate in the blood
5. the patient is a child younger than 2 months old
6. you are taking dofetilide or methenamine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Sulfamethoxazole/Trimethoprim:

Some medical conditions may interact with Sulfamethoxazole/Trimethoprim. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

1. if you are pregnant, planning to become pregnant, or are breast-feeding
2. if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
3. if you have allergies to medicines, foods, or other substances
4. if you have liver or kidney problems,a certain blood problems (eg, anemia, porphyria), thyroid problems, asthma, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or HIV infection
5. if you have low levels of folate in the blood or are at risk for low blood folate levels (eg, you have alcoholism, you are elderly, you do not absorb nutrients from food properly, you are in a poor nutritional state, you are taking medicine for seizures)
6. if you have a history of high blood potassium levels

How to use Sulfamethoxazole/Trimethoprim:

Use sulfamethoxazole/trimethoprim as directed by your doctor. Check the label on the medicine for exact dosing instructions.

1. Sulfamethoxazole/trimethoprim is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using sulfamethoxazole/trimethoprim at home, a health care provider will teach you how to use it. Be sure you understand how to use sulfamethoxazole/trimethoprim. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
2. Do not use sulfamethoxazole/trimethoprim if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
3. Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
4. To clear up your infection completely, use sulfamethoxazole/trimethoprim for the full course of treatment. Keep using it even if you feel better in a few days.
5. If you miss a dose of sulfamethoxazole/trimethoprim, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Sulfamethoxazole and Trimethoprim Dosage.